I am currently enrolled in an undergraduate biochemistry course and have been for about two months. So far (the first 15 chapters), I am very pleased with the textbook. Most explanations are clear, and the illustrations are usually helpful. Also, there are asides that link concepts to real world applications that are interesting. But, I wish the protein chapters included a more comprehensive coverage of motifs.

I had this textbook for Biochem 1 and 2 and I thought it was excellent. It went in-depth when it was needed. The authors choose to leave out some reactions (using multiple arrows) and I thought that was great because it wasn't really needed in most cases. Sometimes there were questions though on how to get to one structure from the last. Pictures were great and really helped to picture what was going on.

I really like this book. It does a great job of explaining the topics in detail, yet not too esoteric that one without a background in either biology or chemistry won't be able to understand. I have neither and I feel I am progressing along well.
The progression of the information content in the chapters makes sense.

I recommend this book.